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USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: O75563




USC-OGP 2-DE database:  O75563

O75563


General information about the entry
View entry in simple text format
Entry nameSKAP2_HUMAN
Primary accession numberO75563
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Src kinase-associated phosphoprotein 2; AltName: Full=Pyk2/RAFTK-associated protein; AltName: Full=Retinoic acid-induced protein 70; AltName: Full=SKAP55 homolog; Short=SKAP-55HOM; Short=SKAP-HOM; AltName: Full=Src family-associated phosphoprotein 2; AltName: Full=Src kinase-associated phosphoprotein 55-related protein; AltName: Full=Src-associated adapter protein with PH and SH3 domains;.
Gene nameName=SKAP2
Synonyms=PRAP, RA70, SAPS, SCAP2, SKAP55R
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

PLATELET_4-5 {PLATELET 4-5}
Homo sapiens (Human)
PLATELET_4-5
  map experimental info 		 
PLATELET_4-5

MAP LOCATIONS:
pI=4.69; Mw=38219
pI=4.63; Mw=38122
pI=4.80; Mw=34013
pI=4.45; Mw=17787

Cross-references
UniProtKB/Swiss-ProtO75563; SKAP2_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameSKAP2_HUMAN
Primary accession numberO75563
Secondary accession number(s) A4D173 Q53GP6 Q75MK6 Q75MZ4 Q9UBZ3 Q9UED8
Sequence was last modified on November 1, 1998 (version 1)
Annotations were last modified on March 15, 2017 (version 137)
Name and origin of the protein
DescriptionRecName: Full=Src kinase-associated phosphoprotein 2; AltName: Full=Pyk2/RAFTK-associated protein; AltName: Full=Retinoic acid-induced protein 70; AltName: Full=SKAP55 homolog; Short=SKAP-55HOM; Short=SKAP-HOM; AltName: Full=Src family-associated phosphoprotein 2; AltName: Full=Src kinase-associated phosphoprotein 55-related protein; AltName: Full=Src-associated adapter protein with PH and SH3 domains;
Gene nameName=SKAP2
Synonyms=PRAP, RA70, SAPS, SCAP2, SKAP55R
Encoded onName=SKAP2; Synonyms=PRAP, RA70, SAPS, SCAP2, SKAP55R
Keywords3D-structure; B-cell activation; Complete proteome; Cytoplasm; Phosphoprotein; Polymorphism; Reference proteome; SH3 domain.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLAB014486; BAA36194.1; -; mRNA
EMBLAJ004886; CAA06193.1; -; mRNA
EMBLAF072166; AAC39924.1; -; mRNA
EMBLAF051323; AAC99296.1; -; mRNA
EMBLAK313209; BAG36025.1; -; mRNA
EMBLAK222885; BAD96605.1; -; mRNA
EMBLAC003999; AAS02033.1; -; Genomic_DNA
EMBLAC011299; AAS07536.1; -; Genomic_DNA
EMBLCH236948; EAL24231.1; -; Genomic_DNA
EMBLCH471073; EAW93859.1; -; Genomic_DNA
EMBLBC002893; AAH02893.1; -; mRNA
EMBLBC036044; AAH36044.1; -; mRNA
CCDSCCDS5400.1; -; .
RefSeqNP_001290397.1; NM_001303468.1; .
RefSeqNP_003921.2; NM_003930.4; .
RefSeqXP_016868260.1; XM_017012771.1; .
UniGeneHs.200770; -; .
UniGeneHs.610137; -; .
UniGeneHs.675700; -; .
PDB3OMH; X-ray; 2.90 A; E/F/G/H=71-79
PDBsum3OMH; -; .
ProteinModelPortalO75563; -; .
SMRO75563; -; .
BioGrid114448; 15; .
IntActO75563; 4; .
STRING9606.ENSP00000005587; -; .
iPTMnetO75563; -; .
PhosphoSitePlusO75563; -; .
BioMutaSKAP2; -; .
OGPO75563; -; .
EPDO75563; -; .
MaxQBO75563; -; .
PaxDbO75563; -; .
PeptideAtlasO75563; -; .
PRIDEO75563; -; .
DNASU8935; -; .
EnsemblENST00000345317; ENSP00000005587; ENSG00000005020; .
GeneID8935; -; .
KEGGhsa:8935; -; .
UCSCuc003syc.4; human; .
CTD8935; -; .
DisGeNET8935; -; .
GeneCardsSKAP2; -; .
H-InvDBHIX0025350; -; .
HGNCHGNC:15687; SKAP2; .
HPAHPA005560; -; .
HPAHPA024045; -; .
MIM605215; gene; .
neXtProtNX_O75563; -; .
OpenTargetsENSG00000005020; -; .
PharmGKBPA162403393; -; .
eggNOGENOG410IH8Q; Eukaryota; .
eggNOGENOG410ZVZV; LUCA; .
GeneTreeENSGT00390000017856; -; .
HOGENOMHOG000231109; -; .
HOVERGENHBG052827; -; .
InParanoidO75563; -; .
OMACFEICAP; -; .
OrthoDBEOG091G0HBY; -; .
PhylomeDBO75563; -; .
TreeFamTF331055; -; .
ReactomeR-HSA-391160; Signal regulatory protein (SIRP) family interactions; .
SignaLinkO75563; -; .
ChiTaRSSKAP2; human; .
GeneWikiSKAP2; -; .
GenomeRNAi8935; -; .
PROPR:O75563; -; .
ProteomesUP000005640; Chromosome 7; .
BgeeENSG00000005020; -; .
CleanExHS_SKAP2; -; .
ExpressionAtlasO75563; baseline and differential; .
GenevisibleO75563; HS; .
GOGO:0005737; C:cytoplasm; IBA:GO_Central; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0005886; C:plasma membrane; IDA:MGI; .
GOGO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc; .
GOGO:0042113; P:B cell activation; IEA:UniProtKB-KW; .
GOGO:0002757; P:immune response-activating signal transduction; IBA:GO_Central; .
GOGO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl; .
GOGO:0006461; P:protein complex assembly; TAS:ProtInc; .
GOGO:0007165; P:signal transduction; TAS:ProtInc; .
Gene3D2.30.29.30; -; 1; .
InterProIPR011993; PH_dom-like; .
InterProIPR001849; PH_domain; .
InterProIPR001452; SH3_domain; .
PfamPF00169; PH; 1; .
PfamPF00018; SH3_1; 1; .
PRINTSPR00452; SH3DOMAIN; .
SMARTSM00233; PH; 1; .
SMARTSM00326; SH3; 1; .
SUPFAMSSF50044; SSF50044; 1; .
SUPFAMSSF50729; SSF50729; 1; .
PROSITEPS50003; PH_DOMAIN; 1; .
PROSITEPS50002; SH3; 1; .


USC-OGP 2-DE database image

Gateways to other related servers

Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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